New technology dramatically improves investigations into traditionally unstable materials
Thuwal, Saudi Arabia – King Abdullah University of Science and Technology (KAUST) signed a worldwide agreement with
Thermo Fisher Scientific that provides the company access to its two patents. These patents have the potential to significantly expand the range of applications for high-resolution transmission electron microscopy (HRTEM). The agreement further establishes KAUST as a premier global technology university, and Saudi Arabia as a regional hub of scientific excellence.
“The exchange of knowledge between the university and industry is an important focus for KAUST and we are always keen to see impact in the economy from the development of our research. We are pleased to work with Thermo Fisher to bring this exciting new technology to the market,” said Kevin Cullen, vice president of
Innovation and Economic Development, KAUST. To understand how atomic structure impacts materials and chemical behavior, researchers often turn to high-resolution transmission electron microscopy (HRTEM). Many compounds, however, are too sensitive for these HRTEM microscopes as powerful electron beams can knock out atoms or cause adverse heating.
KAUST scientists working in the KAUST Core Laboratories embarked on a scientific impact project to overcome such limitations by developing a set of tools that can minimize beam damage in HRTEM using low doses of electrons. These inventions enable atomic-resolution Transmission Electron Microscopy (TEM) imaging of electron beam–sensitive crystalline materials, which have traditionally been considered unsuitable for TEM characterization, dramatically improving investigations in a wide variety of “unstable” materials using HRTEM. “The application of this technology is not limited to beam-sensitive materials, it is also useful for aligning nano-sized crystals. The essence of the image series alignment method is an amplitude filter that facilitates effective and precise alignment of noisy image series containing periodic features and delivers high quality high signal to noise ratio final images.” Said, Dr. Daliang Zhang, senior scientist at KAUST Core Laboratories.
Dr. Zhang, together with other KAUST inventors, Dr. Kun Li, Prof. Yu Han and Dr. Yihan Zhu, have patented the suite of methods that deal with automatic crystal zone axis alignment and precise alignment of noisy image series containing periodic features. The automatic crystal zone axis alignment method not only reduces the electron dose, but also enhances the precision of alignment.
“It’s critical that we collaborate with universities to develop innovative solutions that advance science,” said Trisha Rice, vice president and general manager, materials science, Thermo Fisher Scientific. “Thanks to the KAUST researchers, this new technology will help our customers accelerate materials research and solve complex analytical challenges.” This licensing agreement will strengthen an
already established relationship between KAUST and Thermo Fisher. The KAUST and Thermo Fisher Scientific Center of Excellence for Electron Microscopy, located on the KAUST campus, will facilitate further collaboration in developing and commercializing exciting new technologies to serve science globally.
- By Alexander Buxton, KAUST News
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